Healthy-ageing special: Why blackcurrants are beneficial for the over-50s

Healthy-ageing special: Why blackcurrants are beneficial for the over-50s

AS powerful antioxidants1, blood-flow promoters2,3,4,5 and anti-inflammatory6,7,8 agents, blackcurrants offer fantastic health benefits as we age and are an important ‘purple’ fruit to support longevity and wellbeing.

In this fully referenced article, we explain how blackcurrant's potent compounds can activate the human body’s naturally occurring antioxidant and other defence systems, allowing it to better handle everyday stressors, increased activity and age-related health issues.

Here, we run through some of blackcurrant's spectrum of actions that can benefit the over-50s and support longevity41.



According to the Australian Institute of Health and Welfare9, more than 1 in 4 deaths were due to cardiovascular disease in 2018 and there were more than 1.2 million hospitalisations for cardiovascular disease in 2017-2018. 

Dietary patterns are key culprits in the development of cardiovascular disease10. Studies have suggested that the anthocyanin component of berries11,12,13,14 offer comprehensive protection against a multitude of cardiovascular risk factors. 

Several studies have highlighted that CurraNZ15,16 can offer older adults clinically-relevant cardio-protective effects, by reducing blood pressure, increasing blood flow and making blood vessels healthier.

Just one week’s intake of CurraNZ reduces arterial stiffness16, and can turn back the clock ten years for arterial health. The compounds in CurraNZ naturally help reduce the consequences of ageing on the body’s blood vessels and arteries.



Berries may offer a powerful defence for brain health, with neuro-degenerative decline a huge concern in the ageing population.

Whilst the exact number of Australians suffering from dementia is not known, an estimate puts the figure at between 400,000 and 459,000 (2020). Alzheimer's may account for up to 70% of diagnosed cases.17

Research has shown that the antioxidant properties of blackcurrants, combined with their effect on blood flow and inflammation, are powerful guardians for maintaining memory and cognition44, protecting against cognitive decline in old age and helping keep the brain healthy18,19,20,21,22,23,24,25,25,26,27,28,29.



Anthocyanins and flavonoids in blackcurrants are considered nature’s biological response modifiers. They promote beneficial inflammatory events while helping control and suppress harmful, chronic inflammation31,35,35,36,37,38,39,40.

Chronic inflammation is linked to the development of many serious diseases such as heart disease45,46,47, Type II Diabetes42 and neurodegenerative conditions43, but a healthy diet and lifestyle can help keep inflammation under control. 

The anti-inflammatory and antioxidant properties of blackcurrants are excellent for reducing inflammatory-associated aches and pains, as well as those associated with exercise30, 32,33, 34. Blackcurrants are outstanding for embracing an active lifestyle, whether you’re a keen gardener, runner, golfer, walker, or just love keeping up with the grandchildren.  

The anthocyanins in CurraNZ also increase blood flow2,3,4,5, and reoxygenate tissues during exercise48,49, meaning muscles don’t have to work so hard, suffer less fatigue and can recover more quickly.



The body’s blood vessel network suffers from wear and tear as people get older, with arteries and veins becoming inflamed, clogged with fatty deposits and suffering from general congestion.

Blackcurrant compounds relax the body’s blood vessels2,4,5, thereby allowing for greater circulation and delivery of blood, oxygen and nutrients to all the extremities of the body.

Anthocyanins also reduce inflammatory markers and help maintain the integrity and healthy function of blood vessels8,12,13,14.



The combination and high concentration of red and blue anthocyanins in blackcurrants activate the human body’s naturally occurring antioxidant and other defense systems30,32,33, allowing it to better handle everyday stressors.

Studies have shown they help maintain circulating neutrophil function33, which are the body’s first responders to infection.

By supporting the immune system, blackcurrants help promote the body’s first-line defences which reduce the chance of picking up opportunistic infections, such as colds and flu51.



  1. Antioxidant capacity of small dark fruits: influence of cultivars and harvest time. Kevers C, Pincemail J, Defraigne JO, Dommes J. J Berry Res. doi: 10.3233/JBR-140071
  2. New Zealand Blackcurrant Alters Physiological Reponses and Femoral Artery Diameter during Sustained Isometric Contraction. Matthew David Cook, Stephen David Myers, Mandy Lucinda Gault and Mark Elisabeth Theodorus Willems, June 2017 Nutrients 2017, 9(6), 556; doi:10.3390/nu9060556
  3. Cardiovascular function during Supine Rest in Endurance-Trained Males with New Zealand Blackcurrant: A Dose-Response Study, Matthew David Cook, Stephen David Myers · Mandy Lucinda Gault · Victoria Charlotte Edwards · Mark Elisabeth Theodorus Willems, 1 3Eur J Appl Physiol (2017) 117:247–254DOI 10.1007/s00421-016-3512-x
  4. Upregulation of endothelial nitric oxide synthase by cyanidin-3-glucoside, a typical anthocyanin pigment. Xu JW, Ikeda K, Yamori Y (2004). Hy-pertension 44, 217-222.
  5. Effect of black currant anthocyanins on the activation of endothelial nitric oxide synthase (eNOS) in vitro in human endothelial cells. Edirisinghe I1, Banaszewski K, Cappozzo J, McCarthy D, Burton-Freeman BM. J Agric Food Chem. 2011 Aug 24;59(16):8616-24. doi: 10.1021/jf201116y. Epub 2011 Jul 28.
  6. Molecular targets of dietary polyphenols with anti-inflammatory properties. Yoon JH, Baek SJ. Yonsei Med J. (2005) 46:585–96. doi: 10.3349/ymj.2005.46.5.585
  7. Antioxidant and anti-inflammatory activities of Ribes nigrum extracts. Tabart J, Franck T, Kevers C, et al. Food Chemistry. 2012;131(4):1116–1122.
  8. Anthocyanin-rich blackcurrant extract and cyanidin-3-O-glucoside have cytoprotective and anti-inflammatory properties. Desjardins J1, Tanabe S, Bergeron C, Gafner S, Grenier D. Nat Prod Commun. 2010 Oct;5(10):1613-8.
  10. Nutrition and Cardiovascular Health Int J Mol Sci.2018 Dec; 19(12): 3988. Published online 2018 Dec 11. doi: 3390/ijms19123988
  11. Anthocyanins in Cardiovascular Disease Advances in Nutrition, Volume 2, Issue 1, January 2011, Pages 1–7,
  12. Berry anthocyanins as novel antioxidants in human health and disease prevention. Zafra-Stone S, Yasmin T, Bagchi M, Chatterjee A, Vinson JA, Bagchi D (2007). Mol Nutr Food Res 51 (6):675-683. doi:10.1002/mnfr.200700002
  1. The Effect of Anthocyanin-Rich Foods or Extracts on Vascular Function in Adults: A Systematic Review and Meta-Analysis of Randomised Controlled Trials. Fairlie-Jones L, Davison K, Fromentin E, Hill AM (2017) Nutrients 9 (8). doi:10.3390/nu9080908
  1. Supplementation with orange and blackcurrant juice, but not vitamin E, improves inflammatory markers in patients with peripheral arterial disease.Dalgård C1, Nielsen F, Morrow JD, Enghusen-Poulsen H, Jonung T, Hørder M, de Maat MP. Br J Nutr. 2009 Jan;101(2):263-9. doi: 10.1017/ S0007114508995660. Epub 2008 May 28 
  1. Effect of New Zealand Blackcurrant on Blood Pressure, Cognitive Function and Functional Performance in Older Adults. Journal of Nutrition in Gerontology and Geriatrics (2019) M Cook, A Kaur Sandu, & J Patricia Joyce. DOI: 10.1080/21551197.2019.1707740
  1. Effects of blackcurrant extract on arterial functions in older adults: A randomized, double-blind, placebo-controlled, crossover trial. T Okamoto, Y Hashimoto, R Kobayashi, K Nakazato, M Willems. Journal of Clinical and Experimental Hypertension. (2020)
  1. Supplementation of Blackcurrant Anthocyanins Increased Cyclic Glycine-Proline in the Cerebrospinal Fluid of Parkinson Patients: Potential Treatment to Improve Insulin-Like Growth Factor-1 Function. Dawei Fan, Yassar Alamri, Karen Liu, Michael MacAskill, Paul Harris, Margaret Brimble, John Dalrymple-Alford, Tim Prickett, Oliver Menzies, Andrew Laurenson, Tim Anderson, Jian Guan. Nutrients 2018, 10, 714; doi:10.3390/nu10060714
  2. Anthocyanin-enriched bilberry and blackcurrant extracts modulate amyloid precursor protein processing and alleviate behavioral abnormalities in the APP/PS1 mouse model of Alzheimer’s disease. Vepsäläinen S1, Koivisto H, Pekkarinen E, Mäkinen P, Dobson G, McDougall GJ, Stewart D, Haapasalo A, Karjalainen RO, Tanila H, Hiltunen M. J Nutr Biochem. 2013 Jan;24(1):360-70. doi: 10.1016/j.jnutbio.2012.07.006. Epub 2012 Sep
  3. Effects of anthocyanins and other phenolics of boysenberry and blackcurrant as inhibitors of oxidative stress and damage to cellu-lar DNA in SH-SY5Y and HL-60 cells. Dilip Ghosh1,*, Tony K McGhie2, Jingli Zhang1, Aselle Adaim1 and Margot Skinner1. Journal of the Science of Food and Agriculture Volume 86, Issue 5, pages 678–686, 15 April 2006
  4. Emerging role of polyphenolic compounds in the treatment of neuro¬degenerative diseases: a review of their intracellular targets. Ramassamy, C. (2006) Eur. J. Pharmacol. 545, 51 – 64.
  5. Cytoprotective effects of anthocyanins and other phenolic fractions of Boysenberry and blackcurrant on dopamine and amyloid-induced oxi¬dative stress in transfected COS-7 cells Dilip Ghosh, Tony K McGhie, Derek R Fisher, James A Joseph.Journal of the Science of Food and Agriculture The impact of fruit flavonoids on memory and cognition. Spencer JP. Br J Nutr. 440 2010;104 Suppl 3; S40-7.
  6. Flavonoids and cognition: the molecular mechanisms underlying their behavioural effects. Spencer JP1, Vauzour D, Rendeiro C. Arch Biochem Biophys. 2009 Dec;492(1-2):1-9. doi: 10.1016/ Epub 2009 Oct 12.
  7. The neuroprotective potential of flavonoids: a multiplicity of effects. Vauzour D1, Vafeiadou K, Rodriguez-Mateos A, Rendeiro C, Spencer JP Genes Nutr. 2008 Dec;3(3-4):115-26. doi: 10.1007/s12263-008-0091-4.Brain Res. 2014 Mar 25;1555:60-77. doi: 10.1016/j.brainres.2014.01.047. Epub 2014 Feb 3.
  8. Neuroprotective effects of anthocyanin- and proanthocyanidin-rich extracts in cellular models of Parkinson’s disease.Strathearn KE1, Yousef GG2, Grace MH2, Roy SL1, Tambe MA1, Ferruzzi MG3, Wu QL4, Simon JE4, Lila MA2, Rochet JC5.
  9. Dietary polyphenols as modulators of brain functions: biological actions and molecular mechanisms underpinning their beneficial effects. Vauzour D. Oxid Med Cell Longev. 2012;2012:914273. doi: 10.1155/2012/914273. Epub 2012
  10. Flavonoid intake and cognitive decline over a 10-year period. Letenneur, L., Proust-Lima,C., LeGouge,A., Dartigues, J. F. and Barberger-Gateau, P.(2007) Am. J. Epidemio.165, 1364 – 1371.
  11. 2 Dietary levels of pure flavonoids improve spatial memory performance and increase hippocampal brain-derived neurotrophic factor. Rendeiro C1, Vauzour D, Rattray M, Waffo-Téguo P, Mérillon JM, Butler LT, Williams CM, Spencer JP. PLoS One. 2013 May 28;8(5):e63535. doi: 10.1371/journal. pone.0063535. Print 2013.
  12. Effect of flavonoids on learning, memory and neurocognitive performance: relevance and potential implications for Alzheimer’s disease pathophysiology. Vauzour D. J Sci Food Agric. 2014 Apr;94(6):1042-56. doi: 10.1002/jsfa.6473. Epub 2013 Dec 12.
  13. Daily consumption of NZBCE for five weeks supports recovery through management of Oxidative Stress and inflammation: A Randomized Placebo Controlled Pilot Study. Roger D. Hurst 1, Kirsty A. Lyall 2, Robyn W. Wells 2, Gregory M. Sawyer 1, Dominic Lomiwes 1, Nayer Ngametua1 and Suzanne M. Hurst 1*. Frontiers in Nutrition doi: 10.3389/fnut.2020.00016
  14. Short‑term, but not acute, intake of New Zealand blackcurrant extract improves insulin sensitivity and free‑living postprandial glucose excursions in individuals with overweight or obesity. A. Nolan · R. Brett · J. A. Strauss · C. E. Stewart · S. O. Shepherd,
  15. Short-term blackcurrant extract consumption modulates exercise-induced oxidative stress and lipopolysaccharide-stimulated in-flammatory responses K. A. Lyall, S. M. Hurst, J. Cooney, D. Jensen, K. Lo, R. D. Hurst and L. M.Stevenson Am J Physiol Regulatory Integrative Comp Physiol 297:70-81, 2009. First published Apr 29, 2009;
  16. Consumption of an Anthocyanin-Rich Extract Made From New Zealand Blackcurrants Prior to Exercise may Assist Recovery from Oxidative Stress and Maintains Circulating Neutrophil Function: A Pilot Study Roger D. Hurst 1*, Kirsty A. Lyall 2, Joanna M. Roberts 3, Anton Perthaner 3, Robyn W. Wells 2, Janine M. Cooney 2, Dwayne J. Jensen2, Natalie S. Burr 1 and Suzanne M. Hurst 1*. Frontiers In Nutrition doi: 10.3389/fnut.2019.00073
  17. Blackcurrant nectar reduces muscle damage and inflammation following a bout of high-intensity eccentric contractions. Hutchison, A., Flieller, E., Dillon, K., Leverett, B., Journal of Dietary Supplements, early online release. 1-15 2014.
  18. Oxidative stress and inflammation: what polyphenols can do for us? Hussain T, Tan B, Yin Y, Blachier F, Tossou MC, Rahu N. Oxid Med Cell Longev. (2016) 2016:7432797. doi: 10.1155/2016/7432797
  19. Dietary anthocyanins against obesity and inflammation. Lee YM, Yoon Y, Yoon H, Park HM, Song S, Yeum KJ. Nutrients. (2017) 9:e1089. doi:10.3390/nu9101089
  20. Antioxidant and anti-inflammatory activities of Ribes nigrum extracts. Tabart J, Franck T, Kevers C, et al. Food Chemistry. 2012;131(4):1116–1122.
  21. Polyphenols and inflammation: Basic interactions Curr Opin Clin Nutr Metab Care. 2007 Nov;10(6):724-8. Biesalski HK.
  22. Anthocyanin-rich blackcurrant extract and cyanidin-3-O-glucoside have cytoprotective and anti-inflammatory properties. Desjardins J1, Tanabe S,Bergeron C, Gafner S, Grenier D. Nat Prod Commun. 2010 Oct;5(10):1613-8.
  23. Anthocyanins inhibit nuclear factor-_B activation in monocytes and reduce plasma concentration of pro-inflammatory mediators in healthy adults. Karlsen A, Retterstol L, Laake P, Paur I, Kjolsrud-Bohn S, Sandvik L. J Nutr 137:1951–1954, 2007.
  24. Bioactive Compounds of Edible Fruits with Their Anti-Aging Properties: A Comprehensive Review to Prolong Human Life Antioxidants (Basel).2020 Nov; 9(11): 1123. Published online 2020 Nov 13. doi: 3390/antiox9111123
  25. Duncan BB, Schmidt MI (2006) The epidemiology of low-grade chronic systemic inflammation and type 2 diabetes. Diabetes Technol Ther 8(1):7–17. https ://
  26. Converging pathways in neurodegeneration, from genetics to mechanisms, Nat Neurosci. 2018 Oct; 21(10): 1300–1309.

Published online 2018 Sep 26. doi: 10.1038/s41593-018-0237-7

  1. Watson AW, Haskell-Ramsay CF, Kennedy DO, et al. Acute supplementation with blackcurrant extracts modulates cognitive functioning and inhibits monoamine oxidase-B in healthy young adults. J Funct Foods. 2015;17:524–539. doi:1016/j.jff.2015.06.005.
  2. Inflammation as a therapeutic target in myocardial infarction: learning from past failures to meet future challenges Transl Res. 2016 Jan; 167(1): 152–166.

Published online 2015 Jul 17. doi: 10.1016/j.trsl.2015.07.002

  1. Vascular Inflammation and Oxidative Stress: Major Triggers for Cardiovascular Disease, Oxid Med Cell Longev.2019; 2019: 7092151.

Published online 2019 Jun 23. doi: 10.1155/2019/7092151

  1. New Therapeutic Implications of Endothelial Nitric Oxide Synthase (eNOS) Function/Dysfunction in Cardiovascular Disease Int J Mol Sci. 2019 Jan; 20(1): 187. Published online 2019 Jan 7. doi: 10.3390/ijms20010187
  1. New Zealand blackcurrant extract enhances muscle oxygenation during repeated intermittent forearm muscle contractions in advanced and elite rock climbers, * Simon Fryer1, Dave Giles2, Ellis Bird3, Keeron Stone1, Craig Paterson1, Jiří Baláš4, Mark ET Willems3, Julia A Potter3, Ian C Perkins3. European Journal of Sports Science. DOI:
  1. New Zealand Blackcurrant Extract Enhances Forearm Muscle Oxygenation During and Following Isolated Exhaustive Forearm Exercise in Intermediate-Level Rock Climbers, S Fry, J Potter, I Perkins, C Paterson, M Willems, C Gloucester. International Journal of Sport Nutrition and Exercise Metabolism.
  1. New Zealand Blackcurrant Alters Physiological Reponses and Femoral Artery Diameter during Sustained Isometric Contraction. Matthew David Cook, Stephen David Myers, Mandy Lucinda Gault and Mark Elisabeth Theodorus Willems, June 2017 Nutrients 2017, 9(6), 556; doi:10.3390/nu9060556
  2. The Signaling Pathways, and Therapeutic Targets of Antiviral Agents: Focusing on the Antiviral Approaches and Clinical Perspectives of Anthocyanins in the Management of Viral Diseases, Frontiers in Pharmacology, 2019, doi: 10.3389/fphar.2019.01207
  3. Anti-viral and anti-bacterial activities of an extract of blackcurrants (Ribes nigrum L.), Microbiol Immunol 2012; 56: 805–809 doi:10.1111/j.1348-0421.2012.00510.x