Potential Factors Influencing the Effects of Anthocyanins on Blood Pressure Regulation in Humans: A Review

Synopsis: Dietary intake of anthocyanins (ACNs) is associated with a reduced risk of cardiovascular and coronary heart disease. While the anti-inflammatory, antioxidant, and lipid-lowering effects of ACN consumption have been consistently reported, their effect(s) on blood pressure regulation is less consistent and results from human studies are mixed.

This review assessed 66 human intervention trials testing the effects on blood pressure of purified ACN or ACN-rich extracts, or whole berries, berry juices, powders, purees and whole phenolic extracts, from berries that are rich in ACN and have ACNs as predominant bioactives.

These studies consistingly showed that ACNs act to lower blood pressure when it is higher than normal, but do not lower it when it is already in a healthy range.

Nutrients doi: 10.3390/nu11061431